Season 1

Due to the global pandemic, Dr. Lee has started consulting with her patients through video chat; Monica's big, bumpy birthmark is taking over her neck; Shane has a firm bump precariously near his eye.

Reginald hides the embarrassing growths on the back of his head with knitted hats; Jackie has lived with her huge shoulder lump for nine years.

Fun-loving Che'Re has a squishy, dark bump on her cheek that has left her depressed and self-conscious; Buck has been breaking out in painful, fluid-filled blisters for three years.

Larry has a hanging thigh growth so large that the weight of it makes his leg go numb. Cheerleader Bailee has a disappearing back bump she has named Ralph.

Audrey has a severe condition that leaves her with painful bumps on every inch of her body. An embarrassing armpit growth affects former marine Matt's self-esteem. Jaclyn has a lemon-sized bump on the back of her head.

Roger's case of rhinophyma is so extreme that he has difficulty breathing. The small, evenly spaced bumps all over Natalie's body are interfering with her life.

Shakisaha's earlobe split in half during a failed body modification attempt. After recovering from a flesh-eating disease, Kelly Ann developed a huge leg growth.

Musician Kayla has itchy eczema everywhere, making it difficult to play her guitar. Juan was bullied so badly over the painful bumps he has on his neck and torso that he dropped out of high school.

After being sucker-punched, Dexter developed a large mass that protrudes from his jaw. Zaria hopes her son might avoid the multitude of tiny face bumps that seem to run in her family.

Luke has hundreds of lumps on his body that he has been hiding from his in-laws for over nine years. A trio of skin conditions cause Tanisha tremendous stress.