Determined to save her marriage, Kate tries her hardest to get through to Will - but how will he react when he finds her move to Cardale is a permanent one? Meanwhile Tom and Alex have some unfinished business to sort out and Sam and Kerri begin to cope with the aftermath of the accident.
Bridget oversteps the mark when she gets too close to a patient. Tom and Alex brush of their previous kiss, however Tom's true feelings may be revealed as Alex goes on a date with a GP from a rival practice. Meanwhile as Kerri struggles with her physio, Sam makes a decision that could put their future in jeopardy.
Nick risks his health to pursue his cycling career, whilst Sam gets himself into deeper trouble to pay for Kerri's physio and their impending wedding. Meanwhile Will and Kate clash when their personal problems begin to cloud their work judgement.
The situation between Tom and Alex comes to a head when Tom and Mark clash over a patient. As Sam and Kerri's wedding day approaches, Sam's secret is discovered. Will he stay in Cardale to face the music, and if he leaves will Kerri join him?
Alex becomes unsettled at The Beeches when she continuously falls out with Will and Tom. However is it her surgery partners making her unhappy, or a partner closer to home? Elsewhere, can Kerri's friends help her to recover from the mess Sam has left behind?
As the anniversary of Emily's death approaches, Will and Kate are forced to face some past demons. Can this poignant time bring them closer? Meanwhile Tom gets a new neighbour who is a little more friendly then he'd like.
A charity ball held by the local mayor unites Will, Kate, Tom and Alex. As relations thaw between Will and Kate, is there a chance he could be having second thoughts about their impending divorce? Meanwhile Tom makes his feelings for Alex perfectly clear.
Will offers Kate a place to stay when her house is flooded. Being so close to her again makes Will realise that he is still in love with her - does Kate feel the same? Meanwhile Tom and Alex find it hard to keep professional differences separate from their private lives.
Whilst Will and Kate settle back into married life, Tom and Alex clash over a patient's delicate situation. Meanwhile, Alice comes to the rescue of old friend Billy when his health begins to fail him - is this the start of a beautiful friendship?
Alex's birthday and a visit from her Dad resurfaces some painful memories from the past. Will she and her father be able to rebuild their bridges? Meanwhile is Billy taking Alice for a mug, or is he really very fond of her?
Will faces a tough time when his actions are blamed for a patients death. Alex fears she has the same illness that killed her mother, however as she refuses to let her friends help her, will she have to face the situation on her own?
As news of Alex's illness spreads, Tom finds it increasingly hard to convince her to follow her consultants advice. Will the pressure from friends and colleagues force her to seek solace elsewhere? Meanwhile there's good news for the Pullens when a family treasure brings a little more than luck.
Tom travels to York to find Alex. However she continues to push him away and forces him back to Cardale. The Pullens make a decision about the pub and their future, whilst Will and Kate work hard to stop their jobs interfering with their relationship. Can Will and Kate get over another hurdle and will Alex return to face her illness and Tom?