A rabbit claiming to be the Easter Bunny has been released from the Asylum. As part of his crime wave, he creates a potion to make him large.
Dr. Paul Bunion creates a group of wooden robots in order to pull off a large string of robberies.
A criminal in a bug costume is stealing baby supplies.
Dr. Paul Bunion kidnaps Obediah. With Obediah captured, Pith Possum can't operate anything around Possum Place which enables Dr. Paul Bunion to begin his next plot.
Ralph Bear and Al Dog pose as Pith Possum and Obediah where they go on a crime spree to frame them. Pith Possum and Obediah must capture the imposters even when Doris Deer is captured.
Peter Possum finally scores a date with Doris Deer. This keeps getting ruined with Peter has to become Pith Possum to stop various criminal activities in Possum City.
Displeased that all of Possum City hates bugs, Shirley Pimple enlarges her termites in a plot to destroy all of Possum City.
Super Water Buffalo organizes his own crimes to stop in order to outdo Pith Possum. As each one is stopped, this leads Pith Possum and Obediah to find another line of work.
Pith Possum and Obediah go to a superhero convention in Possum City where they are not taken lightly by the attending superheroes. Pith has the opportunity to turn this around when Dr. Paul Bunion attacks each of the superheroes.
Dr. Paul Bunion enlarges a lizard to gigantic size so that he can have it uproot the trees in Possum City.
Pith Possum gets his by Cranium Crasher Mariachi Cannon and starts acting like different people. Obediah must work to get Pith Possum back to normal when Supper Squirrel raids every food business in Possum City.
Pearl arrives in Possum City to visit her grandson. She starts to defeat some criminals while bringing hardship to Pith Possum and Obediah.
Pith Possum and Obediah take a vacation on a cruise ship called the S.S. Gasbubble. They are unaware that the captain is actually a disguised Dr. Paul Bunion.